[Effects of oral glucose, fructose and saccharose loads on blood sugar, insulin and lipids in normal subjects].

Blood sugar, insulin, NEFA, triglycerides and cholesterol were evaluated in metabolically healthy subjects following oral glucose (100 g in 12 subjects), fructose (50 g in 9 subjects), and saccharose (100 g in 9 subjects). As shown in the literature, glucose led to a slight sugar increase at 60', a marked increase in insulin at 60', and a pronounced fall in NEFA at 120'. Fructose had no effect on sugar and NEFA, whereas there was significant and gradual rise in the insulin curve until 180' (P less than 0.01). In the case of saccharose, the changes in blood sugar, insulin and NEFA were slightly less evident than with glucose. No significant alterations in cholesterol and triglyceride levels were noted throughout the experiment.