Pepeu G
Ann Ist Super Sanita. 1978;14(1):157-62.
Investigations aimed to define the components of the cholinergic network in the cerebral cortex and their functional modifications under the effect of a number of psychotropic drugs are described. By measuring acetylcholine levels and acetylcholine output from the cerebral cortex in cats and rats with various subcortical lesions, at least two systems of cholinergic neurons ascending to the cortex were demonstrated. One of the systems originates from the septum and its activity is affected by drugs acting on dopaminergic receptors.
本文描述了旨在确定大脑皮层胆碱能网络的组成部分及其在多种精神药物作用下功能变化的研究。通过测量患有各种皮层下损伤的猫和大鼠大脑皮层中的乙酰胆碱水平和乙酰胆碱输出量，证实了至少有两个胆碱能神经元系统向皮层上升。其中一个系统起源于隔区，其活动受作用于多巴胺能受体的药物影响。
