Yoneda S, Murata M, Ueda A, Sato M, Takahashi M, Ito T, Sada T, Matsumoto S, Ito Y, Furuta S, Kamiyama A, Akaike A
Clin Cardiol. 1978 Apr;1(1):43-7. doi: 10.1002/clc.4960010107.
A case with persistent atrial standstill is presented which developed from atrial fibrillation associated with rheumatic combined valvular heart disease. In addition to clinical and electrocardiographic findings, electrophysiological and histological studies by using microelectrode technique and electron microscopy, respectively, were carried out on specimens from the right atrial appendage resected at mitral valve surgery. Scattered but severe loss of myocardial cells in the atria and deterioration of the action potential of these poorly sustained myocardial cells were confirmed. The suggestive evidence is also shown that the deteriorated action potential observed by micro-electrode technique in this case may be composed of calcium current.
本文报道了一例持续性心房静止病例，该病例由风湿性联合瓣膜性心脏病伴发的心房颤动发展而来。除临床和心电图检查结果外，还分别采用微电极技术和电子显微镜对二尖瓣手术时切除的右心耳标本进行了电生理和组织学研究。证实心房存在散在但严重的心肌细胞丢失，以及这些存活不佳的心肌细胞动作电位的恶化。同时也有提示性证据表明，该病例中通过微电极技术观察到的动作电位恶化可能由钙电流构成。
