一些吡啶并和吡嗪并苯并咪唑衍生物的合成及其抗真菌活性。
Synthesis of some pyrido- and pyrazino-benzimidazole derivatives and their antifungal activity.
作者信息
Demirayak S, Güven K
机构信息
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Anadolu, Eskişehir, Turkey.
出版信息
Pharmazie. 1995 Aug;50(8):527-9.
PMID:7568315
Abstract
Some 2-aryl-4-hydroxypyrido[1,2-a]benzimidazole and 1-substituted 3-arylpyrazino-[1,2-a]benzimidazole derivatives were synthesized using 1-(2-arylethan-2-on)-2-acylbenzimidazole derivatives as starting materials. Antifungal activities of the compounds obtained were examined in vitro.
摘要
以1-(2-芳基乙-2-酮)-2-酰基苯并咪唑衍生物为起始原料，合成了一些2-芳基-4-羟基吡啶并[1,2-a]苯并咪唑和1-取代-3-芳基吡嗪并[1,2-a]苯并咪唑衍生物。对所得化合物的抗真菌活性进行了体外研究。
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