Baczyński R, Kokot F
Katedry i Nefrologii Slaskiej Akademii Medycznej w Katowicach.
Przegl Lek. 1995;52(6):297-302.
10 patients with renovascular hypertension (HRV) and 12 healthy persons were examined under water immersion (WI) conditions without and after blockade of opioid receptors with 2 mg of naloxone. Blood pressure, body mass, change of plasma volume, plasma molality, PRA, and serum values of AVP, aldosterone and catecholamines were evaluated. There were no significant changes between the two examined groups before and after WI. It seems that the drop in blood pressure induced by WI is not only the result of diminished activation of RAAS. The role of opioid receptors in controlling blood pressure and other evaluated parameters is likely in both examined groups.
对10例肾血管性高血压（HRV）患者和12名健康人在水浸（WI）条件下进行了检查，检查时未使用和使用2毫克纳洛酮阻断阿片受体后。评估了血压、体重、血浆容量变化、血浆摩尔浓度、肾素活性（PRA）以及抗利尿激素（AVP）、醛固酮和儿茶酚胺的血清值。WI前后两个检查组之间没有显著变化。似乎WI引起的血压下降不仅是肾素-血管紧张素-醛固酮系统（RAAS）激活减弱的结果。阿片受体在两个检查组中可能都在控制血压和其他评估参数方面发挥作用。
