Fijałkowska-Morawska J, Kacprzyk F
Kliniki Nefrologii IMW Akademii Medycznej w Lodzi.
Przegl Lek. 1995;52(6):318-22.
In this article new informations about systemic vasculitis were reviewed. Evaluation of ANCA and their antigen specificity is of a great help in classification of systemic vasculitis. Among idiopathic systemic vasculitis anti-serine proteinase antibodies are found in Wegener granuloma, anti-MPO antibodies in Churg-Strauss syndrome and in polyarteritis nodosa. Antibodies against other components of PMNL granules still remain unknown. The main purpose of this review was to underline incidence of systemic vasculitis and the meaning of ANCA in the diagnosis and classification of these diseases.
本文综述了关于系统性血管炎的新信息。抗中性粒细胞胞浆抗体（ANCA）及其抗原特异性的评估对系统性血管炎的分类有很大帮助。在特发性系统性血管炎中，韦格纳肉芽肿病中可发现抗丝氨酸蛋白酶抗体，变应性肉芽肿性血管炎和结节性多动脉炎中可发现抗髓过氧化物酶（MPO）抗体。针对中性粒细胞颗粒其他成分的抗体仍不明确。本综述的主要目的是强调系统性血管炎的发病率以及ANCA在这些疾病诊断和分类中的意义。
