Lawrence J A, Tjornehoj K, Whiteland A P, Kafuwa P T
Project GCP/RAF/259/DEN, Lilongwe 3, Malawi.
Rev Elev Med Vet Pays Trop. 1995;48(1):63-5.
A significant correlation was demonstrated in Friesian-cross steers between the serological response to previous vaccination with the Ball 3 strain of Cowdria ruminantium and the development of protective immunity against the Kalota isolate from Malawi. Of 10 animals which seroconverted after vaccination, all were completely or partially immune to challenge. Ten of the 14 animals which failed to seroconvert were immune but the proportion was not significantly different from that in the unvaccinated controls (4/10). Of 29 animals vaccinated and treated simultaneously with a slow-release doxycycline implant, 13 failed to seroconvert, and of these, four were completely susceptible to challenge.
在弗里斯兰杂交公牛中，针对反刍兽考德里氏体Ball 3株先前疫苗接种的血清学反应与针对马拉维卡洛塔分离株的保护性免疫发展之间存在显著相关性。在接种疫苗后血清转化的10只动物中，所有动物对攻毒完全或部分免疫。14只未发生血清转化的动物中有10只具有免疫力，但该比例与未接种疫苗的对照组（4/10）无显著差异。在29只同时接种疫苗并植入缓释强力霉素的动物中，13只未发生血清转化，其中4只对攻毒完全易感。
