Slezák R, Krejsek J, Kopecký O, Drízhal I
Department of Dentistry, Medical Faculty Charles University.
Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove. 1995;38(1):11-2.
The total white blood cell count, percentage and total count of lymphocytes, CD3+, CD4+, and CD8+ subpopulations of T-lymphocytes, population of CD20+ B-lymphocytes, the ability of polymorphonuclears to phagocyte yeasts, the ability of polymorphonuclear cells to kill serum-resistant strain of E. coli and O2-dependent killing capacity of polymorphonuclears were evaluated in a group of 10 patients with the sicca syndrome and in a group of 9 patients with secondary Sjögren's syndrome and in a healthy control group. There was found a significant decrease in the relative and absolute counts of CD4+ helper/inducer T cells and in the activity of phygocytic cells in both groups of patients with Sjögren's syndrome as compared with the control group. There was no significant difference in the evaluated parameters between primary and secondary Sjögren's syndrome patients.
对10例干燥综合征患者、9例继发性干燥综合征患者及健康对照组进行了如下评估：白细胞总数、淋巴细胞百分比及总数、T淋巴细胞CD3 +、CD4 +和CD8 +亚群、CD20 + B淋巴细胞群、多形核细胞吞噬酵母的能力、多形核细胞杀灭耐血清大肠杆菌菌株的能力以及多形核细胞的O2依赖性杀伤能力。结果发现，与对照组相比，两组干燥综合征患者的CD4 +辅助/诱导性T细胞相对计数和绝对计数以及吞噬细胞活性均显著降低。原发性和继发性干燥综合征患者的评估参数无显著差异。
