Gunnarsson M, Olsson A M
Department of Urology, University Hospital, Lund, Sweden.
Scand J Urol Nephrol. 1995 Jun;29(2):197-205. doi: 10.3109/00365599509180562.
Exploration for microsurgical reconstruction of the vas deferens or its epididymal junction was performed in 47 consecutively treated men. Epididymovasostomy was planned in 27 cases. Malformation was found in five and Young's syndrome in nine, and most of the others had a history of urogenital infections. Reconstruction was accomplished in 17 cases. Nine were azoospermic preoperatively. Four (three with Young's syndrome/malformation) remained so, whereas patency was demonstrated in four and one did not supply a semen specimen postoperatively. Eight had severe unexplained oligozoospermia preoperatively, and in four of them the sperm counts normalized postoperatively while the other four remained oligozoospermic. In no case did preoperative oligozoospermia progress to azoospermia postoperatively. Complete normalization of all spermiogram parameters occurred in only two cases after epididymovasostomy. Of the 20 who underwent reversal of vasectomy, 17 provided semen for postoperative testing. 16/17 specimens contained spermatozoa, but spermiograms, including penetration tests, were completely normal in only three cases. This study indicates a discrepancy between good patency and good semen quality. Our study also suggests that some men with unexplained severe oligozoospermia are as likely to benefit from epididymovasostomy as are azoospermic men.
对47例接受连续治疗的男性进行了输精管或其附睾连接处显微外科重建的探索。计划进行附睾输精管吻合术的有27例。发现5例有畸形,9例有杨氏综合征,其他大多数有泌尿生殖系统感染史。17例完成了重建。9例术前无精子症。4例(3例伴有杨氏综合征/畸形)术后仍无精子症,4例显示通畅,1例术后未提供精液标本。8例术前有严重不明原因少精子症,其中4例术后精子计数恢复正常,另外4例仍为少精子症。术前少精子症术后无一例进展为无精子症。附睾输精管吻合术后仅2例精子图参数完全恢复正常。在20例输精管复通的患者中,17例提供了术后检测的精液。17份标本中有16份含有精子,但只有3例的精子图(包括穿透试验)完全正常。本研究表明通畅良好与精液质量良好之间存在差异。我们的研究还表明,一些不明原因的严重少精子症男性与无精子症男性一样,可能从附睾输精管吻合术中获益。