Tan P K, Tan E C, Tung K H, Foo K T
Department of Surgery, Tan Tock Seng Hospital, Singapore.
Singapore Med J. 1995 Feb;36(1):53-5.
To define a subgroup of staghorn stones that is amenable to extracorporeal shockwave lithotripsy (ESWL) monotherapy and review the need for prophylactic ureteric stents.
Fifty-eight renal units with staghorn calculi in 56 patients (30 males and 26 females) were treated by ESWL monotherapy on the EDAP LT-01 lithotripter. The stones were grouped as complete staghorn (11, 19%), partial staghorn (34, 59%) and borderline staghorn (13, 22%). Results of treatment were analysed in relation to subgroup and calyceal dilatation. Post-treatment complications were studied and the influence of prophylactic ureteric stents examined.
The average number of ESWL sessions was 3.1 (range: 1 to 8). The mean follow-up period was 13 months. Stone-free rate at 10 months was 52%. When clinically insignificant residual fragments less than 4mm were included, the overall clearance rate was 75%. Favourable factors influencing treatment outcome included smaller stone burden, peripheral distribution of stone mass and absence of pelvicalyceal dilatation. The overall complication rate was 39% with urosepsis being the commonest. Complications were related to stone burden. More than half of the renal units with complete staghorn stones developed one or more complications. Auxiliary procedures were required in 18% of the renal units. Twenty of 39 renal units with a stone burden (sum of length and width) greater than 50mm had pretreatment ureteric stenting using the double-J (DJ) siliastic stent. A urosepsis rate of 50% was noted in those with ureteric stents compared to 26% in those not stented. The stents did not offer any advantage in preventing post-treatment obstruction by fragments. Six of 7 renal units with post-treatment obstruction had in-situ stents.
ESWL monotherapy is suitable for selected staghorn stones. Prophylactic ureteric stents do not offer any advantage and may predispose to urosepsis.
确定适合体外冲击波碎石术(ESWL)单一疗法的鹿角形结石亚组,并探讨预防性输尿管支架置入的必要性。
对56例患者(30例男性和26例女性)的58个患有鹿角形结石的肾单位采用EDAP LT - 01碎石机进行ESWL单一疗法治疗。结石分为完全鹿角形(11个,19%)、部分鹿角形(34个,59%)和临界鹿角形(13个,22%)。根据亚组和肾盏扩张情况分析治疗结果。研究治疗后并发症,并检查预防性输尿管支架的影响。
ESWL治疗的平均次数为3.1次(范围:1至8次)。平均随访期为13个月。10个月时的无石率为52%。若将临床意义不大的小于4mm的残留碎片包括在内,总体清除率为75%。影响治疗结果的有利因素包括结石负荷较小、结石块的周边分布以及肾盂肾盏无扩张。总体并发症发生率为39%,其中尿脓毒症最为常见。并发症与结石负荷有关。超过一半的完全鹿角形结石肾单位出现了一种或多种并发症。18%的肾单位需要辅助治疗。在39个结石负荷(长和宽之和)大于50mm的肾单位中,有20个在治疗前使用双J(DJ)硅橡胶支架进行输尿管支架置入。置入输尿管支架者的尿脓毒症发生率为50%,未置入支架者为26%。支架在预防治疗后碎片梗阻方面未显示出任何优势。7个治疗后发生梗阻的肾单位中有6个置入了原位支架。
ESWL单一疗法适用于特定的鹿角形结石。预防性输尿管支架并无优势,且可能易引发尿脓毒症。