人类21号染色体编码的六个表达序列的酵母人工染色体重叠群作图
YAC contig mapping of six expressed sequences encoded by human chromosome 21.
作者信息
Yu J, Cox M, Patterson D, Kao F T
机构信息
Eleanor Roosevelt Institute for Cancer Research, Denver, Colorado 80206, USA.
出版信息
Somat Cell Mol Genet. 1995 Mar;21(2):133-7. doi: 10.1007/BF02255788.
PMID:7570185
Abstract
Six cDNA clones from human chromosome 21 have been mapped in a set of complete YAC contig spanning the entire chromosome 21q. The mapping positions between two STSs on the YAC contig and the NotI coordinates starting from the telomere of 21q were determined for the cDNA clones. The YAC contig mapping positions agree well with those using a comprehensive somatic cell hybrid mapping panel.
摘要
来自人类21号染色体的六个cDNA克隆已被定位到一组跨越整个21号染色体长臂（21q）的完整酵母人工染色体（YAC）重叠群中。对于这些cDNA克隆，确定了YAC重叠群上两个序列标签位点（STS）之间的定位位置以及从21q端粒开始的NotI坐标。YAC重叠群的定位位置与使用全面的体细胞杂种定位板所得到的结果非常吻合。
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