用VLA - 4整合素抑制剂治疗迟发型超敏反应。 - Suppr

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超能文献

Treatment of delayed-type hypersensitivity with inhibitors of the VLA-4 integrin.

作者信息

Tamraz S, Arrhenius T, Chiem A, Forrest M J, Gaeta F C, He Y B, Lei J, Maewal A, Phillips M L, Vollger L W

机构信息

CYTEL Corporation, San Diego, CA 92121, USA.

出版信息

Springer Semin Immunopathol. 1995;16(4):437-41. doi: 10.1007/BF00196099.

DOI:10.1007/BF00196099

PMID:7570294

Abstract

摘要

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Antigen-independent processes in antigen-specific immunity. A role for alpha 4 integrin.抗原特异性免疫中的抗原非依赖过程。α4整合素的作用。

J Immunol. 1993 Feb 15;150(4):1172-82.

A monoclonal antibody recognizing very late activation antigen-4 inhibits eosinophil accumulation in vivo.一种识别极晚期活化抗原-4的单克隆抗体可在体内抑制嗜酸性粒细胞聚集。

J Exp Med. 1993 Feb 1;177(2):561-6. doi: 10.1084/jem.177.2.561.

The integrin VLA-4 mediates leukocyte recruitment to skin inflammatory sites in vivo.整合素VLA - 4在体内介导白细胞募集至皮肤炎症部位。

Clin Exp Rheumatol. 1993 Mar-Apr;11 Suppl 8:S77-80.

Expression and functional significance of alternatively spliced CS1 fibronectin in rheumatoid arthritis microvasculature.类风湿关节炎微血管中可变剪接的CS1纤连蛋白的表达及功能意义

J Clin Invest. 1994 Jan;93(1):405-16. doi: 10.1172/JCI116975.

Dual inhibition of VLA-4 and LFA-1 maximally inhibits cutaneous delayed-type hypersensitivity-induced inflammation.VLA - 4和LFA - 1的双重抑制可最大程度地抑制皮肤迟发型超敏反应诱导的炎症。

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Alpha 4-integrins mediate antigen-induced late bronchial responses and prolonged airway hyperresponsiveness in sheep.α4整合素介导绵羊体内抗原诱导的迟发性支气管反应和持续性气道高反应性。

J Clin Invest. 1994 Feb;93(2):776-87. doi: 10.1172/JCI117032.

CD18-independent neutrophil and mononuclear leukocyte emigration into the peritoneum of rabbits.不依赖CD18的中性粒细胞和单核白细胞向兔腹膜的迁移。

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