Celen H, Boonen S, Pelemans W, Dom R
Diensten Inwendige Geneeskunde, Afdeling Geriatrie en Neurologie, Universitaire Ziekenhuizen, K.U. Leuven.
Tijdschr Gerontol Geriatr. 1995 Aug;26(4):173-7.
Progressive supranuclear palsy (syndrome of Steele-Richardson-Olszewski) represents one of the neuro-degenerative diseases, difficult to distinguish from other forms of parkinsonism. Although uncommon, the syndrome should be included in the differential diagnosis of recurrent falls in the elderly, especially in cases of parkinsonism presenting with axial rigidity and associated with gaze paralysis and/or poor response to L-dopa-therapy. The diagnosis is mainly based on the clinical findings. At present, no effective therapy is known.
进行性核上性麻痹（Steele-Richardson-Olszewski综合征）是一种神经退行性疾病，很难与其他形式的帕金森综合征相区分。尽管并不常见，但在老年人反复跌倒的鉴别诊断中应考虑该综合征，尤其是在出现轴性强直且伴有凝视麻痹和/或对左旋多巴治疗反应不佳的帕金森综合征病例中。诊断主要基于临床表现。目前，尚无已知的有效治疗方法。
