Baldwin D D, Ruckle H C
Division of Urology, Loma Linda University, California 92350, USA.
Urology. 1995 Oct;46(4):570-2. doi: 10.1016/S0090-4295(99)80276-3.
Iatrogenic immunosuppression following renal transplantation has been associated with the development and progression of multiple neoplasms, including transitional cell carcinoma (TCC). We present the first report of invasive TCC of the bladder managed with radical cystectomy in a cardiac transplant recipient. The short survival of this patient, despite organ-confined disease at the time of cystectomy, illustrates the necessity of early diagnosis and aggressive treatment of malignancy following organ transplantation.
肾移植后的医源性免疫抑制与多种肿瘤的发生和进展有关，包括移行细胞癌（TCC）。我们报告了首例心脏移植受者接受根治性膀胱切除术治疗的浸润性膀胱TCC。尽管该患者在膀胱切除时疾病局限于器官内，但生存期较短，这说明了器官移植后恶性肿瘤早期诊断和积极治疗的必要性。
