Corone P, Pauly-Laubry C, Guérin F, Pernot J M, Vernant P, Beer J C, Talon P
Arch Mal Coeur Vaiss. 1977 Sep;70(9):893-9.
714 cases of Fallot's tetralogy have been encountered over the last thirty years. A closed heart operation was undertaken in 472 patients. The mean age at operation was 5,1 years. In 87% of cases, a Blalock-Taussig anastomosis was carried out. The operative mortality was of the order of 3%. The operative risk was almost three times as large before the age of two years as after. The patients benefit by a demonstrable improvement of function after this operation, but it does not protect them from the complications of the condition (cervica abscess, Osler's disease, cerebro-vascular accidents) or from death. Open heart surgery was carried out in 403 patients. 161 as a primary procedure, and 242 after an initial palliative operation. The mean age at operation was 13.3 years. The operative mortality was 15%. The functional improvement was striking, and the patients appeared to be protected from the usual sequelae of the condition. On the other hand they cannot always be considered as cured: 16 died some time after the operation; 37% had pulmonary incompetence; 15% had a residual BSD; 8% had a block of both bundles, and 3% had a definitive atrio-ventricular block.
在过去三十年中,共遇到714例法洛四联症患者。472例患者接受了闭式心脏手术。手术时的平均年龄为5.1岁。87%的病例进行了锁骨下动脉-肺动脉吻合术。手术死亡率约为3%。两岁前的手术风险几乎是两岁后的三倍。患者在接受此手术后功能有明显改善,但这并不能使他们免受该疾病并发症(颈部脓肿、奥斯勒氏病、脑血管意外)或死亡的影响。403例患者接受了心脏直视手术。161例为初次手术,242例在初次姑息手术后进行。手术时的平均年龄为13.3岁。手术死亡率为15%。功能改善显著,患者似乎免受了该疾病常见后遗症的影响。另一方面,他们并不总能被视为治愈:16例在术后一段时间死亡;37%有肺动脉瓣关闭不全;15%有残余室间隔缺损;8%有双束支阻滞,3%有永久性房室阻滞。