Kottkamp H, Chen X, Hindricks G, Willems S, Haverkamp W, Wichter T, Breithardt G, Borggrefe M
Medizinische Klinik und Poliklinik, Westfälische Wilhelms-Universität, Münster.
Z Kardiol. 1995;84 Suppl 2:153-62.
So-called "Mahaim-pathways" represent a distinct subset of accessory pathways and the preexcitation syndromes with unique electrophysiologic properties. During sinus rhythm, preexcitation is minimal or absent whereas incremental atrial stimulation reveals preexcitation with a left bundle branch block like morphology. "Mahaim-fibers" exhibit long conduction times, decremental conduction properties by atrial extrastimuli or incremental atrial pacing, and conduction only in the anterograde direction. The typical atrioventricular reentrant tachycardia incorporating a "Mahaim-pathway" is a preexcited antidromic tachycardia with anterograde conduction over the accessory pathway and retrograde conduction over the AV node. "Mahaim-fibers" may be associated with dual AV node physiology or common atrioventricular accessory pathways. The original concept of "Mahaim-fibers" consisted of accessory pathways originating in the AV node and inserting into the distal right bundle branch ("nodofascicular" pathways) or the right ventricle ("nodoventricular" pathways). This understanding has been challenged by surgical interventions identifying the atrial insertion of "Mahaim-pathways" at the parietal tricuspid annulus. Later, electrophysiologic and surgical studies have confirmed the antero-to posterolateral atrial origin of these accessory pathways remote from the atrioventricular node. Therefore, the concept of nodoventricular pathways has been replaced by the concept of atriofascicular pathways. Recently, endocardial catheter mapping and radiofrequency catheter ablation have substantially contributed to the characterization of this unusual form of the preexcitation syndrome. Distinct, high-frequency activation potentials of atriofascicular accessory pathways can be recorded at the atrial insertion at the antero- to posterolateral tricuspid annulus and along the entire ventricular course up to the ventricular insertion in the right ventricular apical region near or at the distal right bundle branch. The long conduction times and the decremental conduction properties result from a delay in the interval from the local atrial activation at the atrial insertion to the activation potential of the accessory pathway whereas the conduction time between the activation potential of the accessory pathway and the local activation at the ventricular insertion is relatively constant. Overall, the current knowledge about atriofascicular pathways is indicative of a proximal AV-node-like component and a distal bundle-branch-like component and, therefore, suggestive of an accessory AV conduction system. Radiofrequency current application for ablation of atriofascicular pathways can be accomplished at their atrial insertion and along their entire ventricular course. Highfrequency activation potentials of the atriofascicular pathways identify target sites for ablation. Transient mechanical conduction block by catheter manipulation at the subannular level of the atrial insertion has also been introduced as a marker for successful ablation of these unusual accessory pathways.
所谓的“Mahaim 纤维束”是旁路的一个独特子集,是具有独特电生理特性的预激综合征。在窦性心律时,预激很轻微或不存在,而递增性心房刺激可显示出类似左束支传导阻滞形态的预激。“Mahaim 纤维”传导时间长,对心房期外刺激或递增性心房起搏表现出递减传导特性,且仅能进行顺向传导。典型的合并“Mahaim 纤维束”的房室折返性心动过速是一种预激性逆向型心动过速,激动沿旁路顺向传导,经房室结逆向传导。“Mahaim 纤维”可能与房室结双径路生理或普通房室旁路有关。“Mahaim 纤维”的最初概念是指起源于房室结并插入右束支远端(“结-束”纤维束)或右心室(“结-室”纤维束)的旁路。这种认识受到了外科手术的挑战,手术发现“Mahaim 纤维束”的心房插入点位于三尖瓣环壁。后来,电生理和外科研究证实这些旁路起源于远离房室结的心房前壁至后壁区域。因此,“结-室”纤维束的概念已被“房-束”纤维束的概念所取代。最近,心内膜导管标测和射频导管消融术对这种不寻常形式的预激综合征的特征描述有很大帮助。在三尖瓣环前壁至后壁的心房插入点以及沿整个心室走行直至右心室心尖区域靠近或位于右束支远端的心室插入点,均可记录到“房-束”旁路独特的高频激活电位。传导时间长和递减传导特性是由于从心房插入点的局部心房激动到旁路激活电位之间的间隔延迟所致,而旁路激活电位与心室插入点局部激动之间的传导时间相对恒定。总体而言,目前关于“房-束”纤维束的认识表明其具有近端类似房室结的成分和远端类似束支的成分,因此提示存在一个附加的房室传导系统。射频电流应用于“房-束”纤维束的消融可在其心房插入点及其整个心室走行部位进行。“房-束”纤维束的高频激活电位可确定消融靶点。通过在心房插入点瓣环下水平进行导管操作产生的短暂机械性传导阻滞也已被用作这些不寻常旁路成功消融的标志。