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[孕期饮酒母亲所生胎儿(14至15周龄胎儿)大脑发育障碍的动态变化]

[The dynamics of developmental disorders of the brain in fetuses obtained from mothers consuming alcohol during pregnancy (14- to 15-week-old fetuses)].

作者信息

Kovetskiĭ N S, Solonskiĭ A V, Moiseeva T L

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 1995;95(3):58-62.

PMID:7571928
Abstract

By histological method cerebral development was studied in 3 fetus obtained after 14, 14 and 15 weeks to gestation in the mothers abusing alcohol. The excessive plication, invagination and adhesions of the brain wall, porencephalia, abnormal hyperplasia and heterotopia of cells, as well as agenesis of plexus choroideus were detected. These finding were compared with the disturbances in 5- to 12-week-old embryos which had been earlier discovered by authors. It was noted their resemblance, which means the stability of the structural brain changes during ontogenesis.

摘要

采用组织学方法,对3例母亲有酗酒史、妊娠14周、14周和15周后娩出的胎儿的大脑发育情况进行了研究。发现存在脑壁过度折叠、内陷和粘连、孔洞脑、细胞异常增生和异位,以及脉络丛发育不全等情况。将这些发现与作者之前在5至12周龄胚胎中发现的发育障碍进行了比较。注意到它们之间的相似性,这意味着在个体发育过程中大脑结构变化具有稳定性。

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