Majtás J, Springer V
Department of Organization and Management in Pharmacy, Faculty of Pharmacy, Comenius University, Bratislava, Slovak Republic.
Acta Pharm Hung. 1995 Jul;65(4):123-5.
Based on the global hypothesis of drug consumption being a function of human age and growing with its increase, an analysis of that dependence was carried out in the preproductive interval of the human lifetime. The experiment included a total metropolitan population of 450,000, involving all outpatient prescriptions of all physicians in the area. The paper shows results obtained over a period of two years. The methodology, based on the expression of drug consumption in numbers of original package and in terms of financial costs, enabled to formulate the course of this dependence and to define its structure. It was found that preproductive age drug consumption shows a characteristically declining trend, progressively descending from a post-natal maximum to local minimums appearing in the 15-19 year (costs), and 20-24 year (number of packages) age groups, respectively; in addition, it shows sex-specific differences and has the analytical shape of a 2nd degree polynomial. After the local minimums the curve begins to ascend according to the characteristic trend in the productive period of the human lifetime.
基于药物消费是人类年龄的函数且随年龄增长而增加这一总体假设，在人类生命周期的生育前期对这种依赖性进行了分析。该实验涵盖了总计45万的大都市人口，涉及该地区所有医生的所有门诊处方。本文展示了两年期间获得的结果。该方法基于以原包装数量和财务成本来表达药物消费，从而能够确定这种依赖性的变化过程并界定其结构。研究发现，生育前期的药物消费呈现出典型的下降趋势，从出生后的最大值逐渐下降，分别在15 - 19岁（成本）和20 - 24岁（包装数量）年龄组出现局部最小值；此外，它还表现出性别差异，并且具有二次多项式的分析形状。在局部最小值之后，曲线开始按照人类生命周期生育期的特征趋势上升。
