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母马胚胎移植术后前列腺素F2α代谢物水平

Prostaglandin F2 alpha metabolite levels following an embryo transfer procedure in the mare.

作者信息

Kask K, Malmgren L, Odensvik K

机构信息

Department of Obstetrics and Gynaecology, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, Uppsala.

出版信息

Acta Vet Scand. 1995;36(1):145-7. doi: 10.1186/BF03547711.

DOI:10.1186/BF03547711
PMID:7572452
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8095418/
Abstract

Hormonal, chemical, and mechanical stimuli can activate the arachidonic acid cascade and result in formation of prostaglandins and related substances. These compounds can have a profound role in the initiation of the inflammatory process ( 1984). Prostaglandin (PG) F is the key hormone in reproductive physiology with well-known effects on reproductive performance e.g. luteolysis and abortion. An activation of the arachidonic acid cascade, caused by mechanical manipulation during an embryo transfer procedure, might be one explanation for early embryonic loss.

摘要

激素、化学和机械刺激可激活花生四烯酸级联反应，导致前列腺素及相关物质的形成。这些化合物在炎症过程的起始中可能起重要作用（1984年）。前列腺素（PG）F是生殖生理学中的关键激素，对生殖性能有众所周知的影响，例如黄体溶解和流产。胚胎移植过程中的机械操作引起的花生四烯酸级联反应激活，可能是早期胚胎丢失的一种解释。

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本文引用的文献

1
Radioimmunoassay of the major plasma metabolite of PGF2 alpha, 15-keto-13,14-dihydro-PGF2 alpha.
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The acute inflammatory process, arachidonic acid metabolism and the mode of action of anti-inflammatory drugs.急性炎症过程、花生四烯酸代谢与抗炎药物的作用方式。
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