[Pregnancy in hereditary enzymatic methemoglobinemia].

The authors describe a case of successful pregnancy in a patent with hereditary enymopenic methemoglobinemia. The course of pregnancy was followed up by the use of ultrasound and the control of CTG, estriol, and pregnanediol. No signs of the intrauterine fetal threat were noticed. The methemoglobin value in the mother's blood ranged from 6.4% at the beginning of pregnancy to 32% at delivery, going down to 2.2% on the third postpartal day. Its reduction was increased by 2.0 to 3.0 g of C vitamin a day throughout all the time of pregnancy. The use of drugs with reduction properties is contraindicated. Genetic analysis of both parents is imperative, because a homozygote newborn could suffer from convulsions. Under conditions of present-day perinatal supervision and adequate therapy, hereditary enzymopenic methemoglobinemia is no contraindication for the performance of the reproductive function.