Födinger M, Speiser W, Karabentcheva S, Scherrer R, Veitl M, Schwarzinger I
Department of Laboratory Medicine, University of Vienna, Austria.
Am J Clin Pathol. 1995 Nov;104(5):503-9. doi: 10.1093/ajcp/104.5.503.
In this study, the authors evaluated a closed tube total hematology analysis system, Sysmex HS-430 (HS), which consists of two automated hematology analyzers, Sysmex NE-8000, the reticulocyte analyzer, Sysmex R-3000, and a slide preparation unit integrated in an automated sample transport system (TOA Medical Electronics, Kobe, Japan). The suitability of the system was compared with a conventional hematology system (CS) consisting of two single standing Coulter STKS analyzers (Hialeah, FL), one automated reticulocyte counter Sysmex R-1000, and the manual blood smear preparation. Evaluation was performed following the concept suggested by the Austrian-German societies for Clinical Chemistry and Laboratory Medicine that includes the evaluation of personnel supply. Eight consecutive series with a total of 4,896 samples were analyzed on both systems. Evaluation revealed that the analysis time per series was 238 minutes on the HS-430 and 359 minutes on the CS. The mean analyzer down times because of technical reasons were 36 minutes on the HS and 32 minutes on the CS. The down time because of "nontechnical" reasons was 31 minutes on the HS-430, but 173 minutes on the CS, which was mainly because of discontinuous sample loading of analyzers of the CS. The average direct technical time effort for complete blood cell count (CBC) analyses, reticulocyte counts, and blood smear preparations per series was 23 minutes on the HS and 245 minutes on the CS. In summary, these data show that an automated system like the HS-430 saves 222 minutes of manual activities arising in a large routine hematology laboratory with a mean throughout of 612 samples per day. Furthermore, the system improves intralaboratory turnaround times, avoids human errors by automated sample identification, and guarantees more safety for laboratory staff by minimizing the contact with potential biohazards.
在本研究中，作者评估了一种封闭式全血细胞分析系统，即Sysmex HS - 430（HS），该系统由两台自动血液分析仪Sysmex NE - 8000、网织红细胞分析仪Sysmex R - 3000以及集成在自动样本传输系统中的玻片制备单元组成（日本神户东亚医疗电子公司）。将该系统的适用性与传统血液学系统（CS）进行了比较，传统血液学系统由两台独立的库尔特STKS分析仪（佛罗里达州希亚莱）、一台自动网织红细胞计数器Sysmex R - 1000以及手工血涂片制备组成。按照奥地利 - 德国临床化学和检验医学学会提出的概念进行评估，其中包括对人员配备的评估。在这两个系统上对连续8个系列共4896个样本进行了分析。评估结果显示，HS - 430每个系列的分析时间为238分钟，而CS为359分钟。由于技术原因，HS系统分析仪的平均停机时间为36分钟，CS系统为32分钟。HS - 430因“非技术”原因的停机时间为31分钟，而CS为173分钟，这主要是由于CS系统分析仪的样本加载不连续。每个系列进行全血细胞计数（CBC）分析、网织红细胞计数和血涂片制备的平均直接技术时间投入，HS系统为23分钟，CS系统为245分钟。总之，这些数据表明，像HS - 430这样的自动化系统在一个日均通量为612个样本的大型常规血液学实验室中，可节省222分钟的手工操作时间。此外，该系统缩短了实验室内部的周转时间，通过自动样本识别避免了人为错误，并通过尽量减少与潜在生物危害的接触为实验室工作人员提供了更多安全保障。
