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早期乳腺癌的治疗:与保乳手术相关的医院特征

Treating early-stage breast cancer: hospital characteristics associated with breast-conserving surgery.

作者信息

Johantgen M E, Coffey R M, Harris D R, Levy H, Clinton J J

机构信息

Agency for Health Care Policy and Research, Center for General Health Services Intramural Research, Rockville, MD 20852, USA.

出版信息

Am J Public Health. 1995 Oct;85(10):1432-4. doi: 10.2105/ajph.85.10.1432.

DOI:10.2105/ajph.85.10.1432
PMID:7573632
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1615611/
Abstract

Despite growing acceptance of the fact that women with early-stage breast cancer have similar outcomes with lumpectomy plus radiation as with mastectomy, many studies have revealed the uneven adoption of such breast-conserving surgery. Discharge data from the Hospital Cost and Utilization Project, representing multiple payers, locations, and hospital types, demonstrate increasing trends in breast-conserving surgery as a proportion of breast cancer surgeries from 1981 to 1987. Women with axillary node involvement were less likely to have a lumpectomy, even though consensus recommendations do not preclude this form of treatment when local metastases are present. Non-White race, urban hospital location, and hospital teaching were associated with an increased likelihood of having breast-conserving surgery.

摘要

尽管早期乳腺癌女性接受保乳手术加放疗与乳房切除术的治疗效果相似这一事实已越来越被认可,但许多研究表明,这种保乳手术的采用情况并不均衡。来自医院成本与利用项目的出院数据涵盖了多个支付方、地点和医院类型,这些数据显示,从1981年到1987年,保乳手术在乳腺癌手术中所占比例呈上升趋势。即使存在局部转移时,共识性建议并不排除这种治疗方式,但腋窝淋巴结受累的女性接受保乳手术的可能性较小。非白人种族、城市医院所在地以及医院教学性质与接受保乳手术的可能性增加相关。

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本文引用的文献

1
Five-year results of a randomized clinical trial comparing total mastectomy and segmental mastectomy with or without radiation in the treatment of breast cancer.一项比较全乳切除术与保乳手术加或不加放疗治疗乳腺癌的随机临床试验的五年结果。
N Engl J Med. 1985 Mar 14;312(11):665-73. doi: 10.1056/NEJM198503143121101.
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Hospital variables associated with quality of care for breast cancer patients.与乳腺癌患者护理质量相关的医院变量。
JAMA. 1991 Dec 25;266(24):3429-32.
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Nonclinical factors associated with surgery received for treatment of early-stage breast cancer.与早期乳腺癌治疗手术相关的非临床因素。
Am J Public Health. 1992 Feb;82(2):195-8. doi: 10.2105/ajph.82.2.195.
6
Regional differences in surgical management of breast cancer.乳腺癌手术治疗的区域差异。
CA Cancer J Clin. 1992 Jan-Feb;42(1):39-43. doi: 10.3322/canjclin.42.1.39.
7
Underutilization of breast-conserving surgery and radiation therapy among women with stage I or II breast cancer.I期或II期乳腺癌女性中保乳手术和放射治疗的利用不足。
JAMA. 1991 Dec 25;266(24):3433-8.
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Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases.调整临床合并症指数以用于ICD-9-CM管理数据库。
J Clin Epidemiol. 1992 Jun;45(6):613-9. doi: 10.1016/0895-4356(92)90133-8.
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N Engl J Med. 1992 Apr 23;326(17):1097-101. doi: 10.1056/NEJM199204233261701.