Parent X, Ait Hmad Z, Aberer P
Laboratoire de biochimie, centre hospitalier Louis-Pasteur, Colmar, France.
Ann Biol Clin (Paris). 1995;53(1-2):11-3.
The effect of storage of samples on the assay of lipoprotein(a) depends on the technique used. We have tested the automated Beckman 360 Array rate nephelometer using Dako anti-Lp(a) antibody, and an Immunofrance standard and control serum according to the technique of Gillery et al. We found a very high correlation between serum concentrations before freezing and those after three weeks and six months at -80 degrees C. Variations greater than 15% concerned only low levels of Lp(a) and were probably related to the precision of the technique at low concentrations.
样本储存对脂蛋白(a)检测的影响取决于所使用的技术。我们根据吉利里等人的技术，使用达科抗Lp(a)抗体、免疫法国标准品和对照血清，对贝克曼360全自动速率散射比浊仪进行了测试。我们发现，在-80℃下冷冻前和冷冻三周及六个月后的血清浓度之间存在非常高的相关性。大于15%的变化仅涉及低水平的Lp(a)，可能与该技术在低浓度下的精密度有关。
