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[肝动脉灌注化疗预防结直肠癌肝切除术后肝转移的研究]

[Study of hepatic arterial infusion chemotherapy for prophylaxis of liver metastases of colorectal cancer after hepatic resection].

作者信息

Hanada H, Umekita N, Maeshiro T, Miyamoto S, Yamada F, Awane Y

机构信息

Dept. of Surgery, Tokyo Metropolitan Bokutou Hospital.

出版信息

Gan To Kagaku Ryoho. 1995 Sep;22(11):1497-9.

PMID:7574742
Abstract

We examined the significance of hepatic arterial infusion chemotherapy (HAIC) for prophylaxis of liver metastases of colorectal cancer after hepatic resection using an implantable port. Fifty-five patients operated at the hospital from August 1988 to December 1994 were divided into two groups consisting of 23 patients with HAIC group: (HAIC (+)), and 32 patients without HAIC group: (HAIC (-)) retrospectively. The cumulative survival rates and recurrent rates of cancer free in remnant liver of HAIC (+) were improved, compared with HAIC (-). This suggests that HAIC was effective in improving the prognosis and preventing recurrence in remnant liver.

摘要

我们使用植入式端口研究了肝动脉灌注化疗(HAIC)对结直肠癌肝切除术后肝转移预防的意义。回顾性分析了1988年8月至1994年12月在我院接受手术的55例患者,分为两组:HAIC组(HAIC(+))23例,非HAIC组(HAIC(-))32例。与HAIC(-)组相比,HAIC(+)组的累积生存率和残余肝无癌复发率有所提高。这表明HAIC对改善预后和预防残余肝复发有效。

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