Simon G E, VonKorff M, Barlow W
Center for Health Studies, Group Health Cooperative of Puget Sound, Seattle, Wash, USA.
Arch Gen Psychiatry. 1995 Oct;52(10):850-6. doi: 10.1001/archpsyc.1995.03950220060012.
While an extensive literature documents the influence of depression on general medical services utilization, estimates of the economic burden of depression have focused on the direct costs of depression treatment. Higher use of general medical services may contribute significantly to the true cost of depressive illness.
Computerized record systems of a large staff-model health maintenance organization (HMO) were used to identify consecutive primary care patients with visit diagnoses of depression (n = 6257) and a comparison sample of primary care patients with no depression diagnosis (n = 6257). The HMO accounting records were used to compare components of health care costs.
Patients diagnosed as depressed had higher annual health care costs ($4246 vs $2371, P < .001) and higher costs for every category of care (eg, primary care, medical specialty, medical inpatient, pharmacy, laboratory). Similar cost differences were observed for each of the subgroups examined (patients treated with antidepressants, those not treated with antidepressants, and those diagnosed at routine physical examination visits). Pharmacy records indicated greater chronic medical illness in the diagnosed depression group, but large cost differences remained after adjustment ($3971 vs $2644). Twofold cost differences persisted for at least 12 months after initiation of treatment.
Diagnosis of depression is associated with a generalized increase in use of health services that is only partially explained by comorbid medical conditions. In the primary care sector, this greater medical utilization exceeds direct treatment costs for depression. The persistence of utilization differences suggests that recognition and initiation of treatment alone are not adequate to reduce utilization differences.
尽管大量文献记载了抑郁症对一般医疗服务利用的影响,但对抑郁症经济负担的估计主要集中在抑郁症治疗的直接成本上。一般医疗服务的更高使用量可能对抑郁症的实际成本有重大影响。
利用一个大型员工模式健康维护组织(HMO)的计算机化记录系统,识别出连续的被诊断患有抑郁症的初级保健患者(n = 6257)以及未被诊断患有抑郁症的初级保健患者对照样本(n = 6257)。使用HMO的会计记录来比较医疗保健成本的组成部分。
被诊断为抑郁症的患者年度医疗保健成本更高(4246美元对2371美元,P <.001),并且各类医疗保健的成本都更高(例如初级保健、医学专科、住院医疗、药房、实验室)。在检查的每个亚组中都观察到了类似的成本差异(接受抗抑郁药治疗的患者、未接受抗抑郁药治疗的患者以及在常规体检就诊时被诊断出的患者)。药房记录表明,被诊断为抑郁症的组中慢性疾病更多,但调整后仍存在较大的成本差异(3971美元对2644美元)。治疗开始后至少12个月,成本差异一直保持在两倍。
抑郁症的诊断与医疗服务使用的普遍增加相关,而合并的医疗状况只能部分解释这种情况。在初级保健部门,这种更高的医疗利用率超过了抑郁症的直接治疗成本。利用率差异的持续存在表明,仅识别和开始治疗不足以减少利用率差异。