Simon G, Ormel J, VonKorff M, Barlow W
Center for Health Studies, Group Health Cooperative, Seattle, WA 98101-1448.
Am J Psychiatry. 1995 Mar;152(3):352-7. doi: 10.1176/ajp.152.3.352.
The authors examined the overall health care costs associated with depression and anxiety among primary care patients.
Of 2,110 consecutive primary care patients in a health maintenance organization, 1,962 were screened with the 12-item General Health Questionnaire. A stratified random sample of 615 patients were selected for further diagnostic assessment; 373 of these patients completed the Composite International Diagnostic Interview at baseline and 328 were reassessed 12 months later. Computerized cost records were used to calculate total health care costs for the 6-month period surrounding the baseline assessment and a similar period surrounding the follow-up assessment. Cost accounting data were available for 327 patients at baseline and for 206 patients at both assessments.
Primary care patients with DSM-III-R anxiety or depressive disorders at baseline had markedly higher baseline costs ($2,390) than patients with subthreshold disorders ($1,098) and those with no anxiety or depressive disorder ($1,397). Large cost differences persisted after adjustment for medical morbidity. Cost differences reflected higher utilization of general medical services rather than higher mental health treatment costs. Although most patients with baseline anxiety or depressive disorders showed significant improvement, longitudinal analyses did not show any clear relationship between change in psychiatric diagnosis and change in health care cost.
Among primary care patients, anxiety and depressive disorders are associated with markedly higher health care costs even after adjustment for medical comorbidity. In this small sample, improvement in depression over 1 year was not clearly associated with decreases in cost.
作者研究了初级保健患者中与抑郁和焦虑相关的总体医疗保健成本。
在一家健康维护组织中,对2110名连续的初级保健患者进行了研究,其中1962名患者接受了12项一般健康问卷的筛查。从这些患者中选取了615名进行分层随机抽样,以进行进一步的诊断评估;其中373名患者在基线时完成了综合国际诊断访谈,328名患者在12个月后接受了重新评估。利用计算机化成本记录计算基线评估前后6个月期间以及随访评估前后类似期间的总医疗保健成本。在基线时可获得327名患者的成本核算数据,在两次评估时均可获得206名患者的成本核算数据。
基线时患有DSM-III-R焦虑或抑郁障碍的初级保健患者的基线成本(2390美元)明显高于患有阈下障碍的患者(1098美元)和没有焦虑或抑郁障碍的患者(1397美元)。在对医疗发病率进行调整后,成本差异仍然很大。成本差异反映了一般医疗服务的利用率较高,而不是心理健康治疗成本较高。尽管大多数基线时患有焦虑或抑郁障碍的患者有显著改善,但纵向分析并未显示精神疾病诊断变化与医疗保健成本变化之间有任何明确的关系。
在初级保健患者中,即使对医疗合并症进行调整后,焦虑和抑郁障碍仍与明显更高的医疗保健成本相关。在这个小样本中,1年内抑郁症状的改善与成本降低并没有明显关联。