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针对与中间葡萄膜炎相关的新生血管形成的周边散射光凝术。

2 peripheral scatter photocoagulation for neovascularization associated with pars planitis.

作者信息

Park S E, Mieler W F, Pulido J S

机构信息

Department of Ophthalmology, Medical College of Wisconsin, Milwaukee, USA.

出版信息

Arch Ophthalmol. 1995 Oct;113(10):1277-80. doi: 10.1001/archopht.1995.01100100065030.

Abstract

BACKGROUND

Peripheral cryotherapy appears to be efficacious in the treatment of neovascularization of the vitreous base in patients with pars planitis, although it may be associated with the development of rhegmatogenous retinal detachments.

OBJECTIVE

To evaluate the safety and efficacy of peripheral scatter photocoagulation for treatment of neovascularization of the vitreous base when used alone or combined with pars plana vitrectomy.

METHODS

Six patients (10 eyes) presented with vitritis, cystoid macular edema, and neovascularization of the vitreous base, unresponsive to corticosteroid therapy. Three patients (five eyes) received scatter diode or argon photocoagulation treatment alone. The other three patients (five eyes) underwent pars plana vitrectomy coupled with argon or diode photocoagulation, placed in three rows, posterior to the area of inferior neovascularization of the vitreous base.

RESULTS

Pretreatment visual acuity ranged from 20/20 to 20/200. All patients were followed up for a minimum of 6 months. After placement of photocoagulation (with or without concurrent pars plana vitrectomy), the neovascularization regressed, inflammation was stabilized, and cystoid macular edema improved in all eyes. There were no retinal detachments or other complications of treatment. Posttreatment visual acuity ranged from 20/20 to 20/100. When final visual acuity was 20/40 or less, cataract formation was generally responsible.

CONCLUSIONS

Peripheral scatter photocoagulation is efficacious and appears at least equal to peripheral cryotherapy in causing regression of neovascularization of the vitreous base in patients with pars planitis.

摘要

背景

周边部冷冻疗法在治疗中间葡萄膜炎患者的玻璃体基底部新生血管方面似乎有效,尽管它可能与孔源性视网膜脱离的发生有关。

目的

评估单独使用或联合玻璃体切除术时周边部散射光凝治疗玻璃体基底部新生血管的安全性和有效性。

方法

6例患者(10只眼)出现葡萄膜炎、黄斑囊样水肿和玻璃体基底部新生血管,对皮质类固醇治疗无反应。3例患者(5只眼)仅接受散射二极管或氩激光光凝治疗。另外3例患者(5只眼)接受玻璃体切除术联合氩激光或二极管光凝,光凝位于玻璃体基底部下方新生血管区域后方,分三排进行。

结果

治疗前视力范围为20/20至20/200。所有患者至少随访6个月。进行光凝(无论是否同时行玻璃体切除术)后,所有眼的新生血管消退,炎症稳定,黄斑囊样水肿改善。未发生视网膜脱离或其他治疗并发症。治疗后视力范围为20/20至20/100。当最终视力为20/40或更低时,通常是白内障形成所致。

结论

周边部散射光凝有效,在导致中间葡萄膜炎患者玻璃体基底部新生血管消退方面似乎至少与周边部冷冻疗法等效。

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