Mateos V, Salas-Puig J, Campos D M, Tuñón A, Roiz C, Lahoz C H
Servicio de Neurología, Hospital General de Asturias, Oviedo.
Neurologia. 1995 Aug-Sep;10(7):298-301.
Periodic lateralized epileptiform discharges (PLEDs) in an EEG usually indicate the presence of an underlying structural lesion (of vascular origin in most cases). PLEDs are also sometimes observed in certain types of infections (mainly viral), in which they may even constitute a characteristic finding useful for diagnostic purposes. In recent years cases have been reported in which PLEDs are linked to recurring confusional states that do not fit in with established classifications and that may be epileptic in nature. We discuss the cases of 2 patients who were repeatedly admitted to our hospital in confusional states, in whom PLEDs were observed in EEG readings. Clinical evolution in both cases paralleled EEG alterations. We were able to perform both critical and intercritical single proton emission tomography on 1 patient, finding, respectively, hyper- and hypoabsorption foci. Symptoms resolved with antiepileptic treatment.
脑电图中的周期性一侧性癫痫样放电（PLEDs）通常提示存在潜在的结构性病变（大多数情况下为血管源性）。PLEDs有时也见于某些类型的感染（主要是病毒感染），在这些感染中它们甚至可能是有助于诊断的特征性表现。近年来，有报道称PLEDs与不符合既定分类且可能具有癫痫性质的反复意识模糊状态有关。我们讨论了2例反复因意识模糊状态入住我院的患者病例，其脑电图检查发现有PLEDs。两例患者的临床病程均与脑电图改变平行。我们对其中1例患者进行了发作期和发作间期单光子发射断层扫描，分别发现了高摄取和低摄取灶。症状通过抗癫痫治疗得以缓解。
