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[细胞周期不同阶段细胞某些物理特性的变化]

[Change in certain physical characteristics of cells at various stages of the cell cycle].

作者信息

Samoĭlova O P, Tsapin A I, Bliumenfel'd L A

出版信息

Biofizika. 1995 Mar-Apr;40(2):383-8.

PMID:7578343
Abstract

Experiments on semisynchronized cultures of animal and plant cells, performed in our laboratory approximately 30 years ago, have demonstrated that there exist regular changes of certain physical parameters of the cells during the cell cycle. In particular on yeast cultures there has been observed the appearance of specific electron paramagnetic resonance (EPR) signals with simultaneous change of the static magnetic susceptibility of the cultures in the period immediately preceding the beginning of the intensive budding. On chlorella cultures grown at certain regimes of light and darkness it is possible to observe characteristic changes of the kinetics of the photoconduction signal at the frequency of 10 HHz (SHR-photoconduction). It can be conjectured that these effects are of a similar nature linked to some changes of the intracellular structures at certain stages of the cell cycle. The work performed much later makes it possible to link these changes to the appearance of spin, glass-like structures in macromolecular intracellular bodies.

摘要

大约30年前在我们实验室进行的关于动植物细胞半同步培养的实验表明,在细胞周期中细胞的某些物理参数存在规律性变化。特别是在酵母培养物中,在密集出芽开始前的一段时间内,观察到了特定电子顺磁共振(EPR)信号的出现,同时培养物的静态磁化率也发生了变化。在以特定光照和黑暗条件培养的小球藻培养物中,可以观察到频率为10赫兹(SHR-光电导)的光电导信号动力学的特征变化。可以推测,这些效应具有相似的性质,与细胞周期特定阶段细胞内结构的某些变化有关。后来进行的研究使我们能够将这些变化与细胞内大分子物体中自旋、玻璃状结构的出现联系起来。

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