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Cloning and sequence of the feline max, and max 9 transcripts.

作者信息

Gallagher R C, Neil J C, Fulton R

机构信息

Department of Veterinary Pathology, University of Glasgow Veterinary School.

出版信息

DNA Seq. 1995;5(5):269-71. doi: 10.3109/10425179509030979.

DOI:10.3109/10425179509030979
PMID:7579579
Abstract

Max is the recently discovered heterodimeric partner of the human myc oncogene product. In this report we describe the cloning and sequencing of two differentially spliced transcripts of the feline max gene. Previously published data have shown both myc and max to be highly conserved amongst species, and indeed there is a 100% homology between feline max and max, while the murine equivalent myn is 98% homologous at the amino acid level, with the nucleotide sequences showing a similarity of 98% and 95% respectively.

摘要

相似文献

1
Cloning and sequence of the feline max, and max 9 transcripts.
DNA Seq. 1995;5(5):269-71. doi: 10.3109/10425179509030979.
2
Variant Max protein, derived by alternative splicing, associates with c-Myc in vivo and inhibits transactivation.通过可变剪接产生的变体Max蛋白在体内与c-Myc结合并抑制反式激活。
Mol Cell Biol. 1995 Dec;15(12):6702-9. doi: 10.1128/MCB.15.12.6702.
3
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EMBO J. 1999 Dec 15;18(24):7019-28. doi: 10.1093/emboj/18.24.7019.
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Mmip1: a novel leucine zipper protein that reverses the suppressive effects of Mad family members on c-myc.Mmip1:一种新型亮氨酸拉链蛋白,可逆转Mad家族成员对c-myc的抑制作用。
Oncogene. 1998 Mar 5;16(9):1149-59. doi: 10.1038/sj.onc.1201634.
5
Differential expression of max and two types of c-myc genes in a tetraploid fish, the common carp (Cyprinus carpio).
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6
Discrimination between different E-box-binding proteins at an endogenous target gene of c-myc.在c-myc的内源性靶基因处对不同E盒结合蛋白的区分。
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7
Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc.Max:一种螺旋-环-螺旋拉链蛋白,可与Myc形成序列特异性DNA结合复合物。
Science. 1991 Mar 8;251(4998):1211-7. doi: 10.1126/science.2006410.
8
Overexpression of Mxi1 inhibits the induction of the human ornithine decarboxylase gene by the Myc/Max protein complex.Mxi1的过表达抑制了Myc/Max蛋白复合物对人鸟氨酸脱羧酶基因的诱导作用。
Oncogene. 1996 Feb 1;12(3):621-9.
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Both the helix-loop-helix and the leucine zipper motifs of c-Myc contribute to its dimerization specificity with Max.c-Myc的螺旋-环-螺旋基序和亮氨酸拉链基序都有助于其与Max的二聚化特异性。
Oncogene. 1993 Jan;8(1):125-32.
10
Mxi2, a mitogen-activated protein kinase that recognizes and phosphorylates Max protein.Mxi2,一种识别并磷酸化Max蛋白的丝裂原活化蛋白激酶。
Proc Natl Acad Sci U S A. 1995 Nov 7;92(23):10531-4. doi: 10.1073/pnas.92.23.10531.

引用本文的文献

1
The role of polymerase chain reaction and its newer developments in feline medicine.聚合酶链反应的作用及其在猫科医学中的新进展。
J Feline Med Surg. 1999 Jun;1(2):89-100. doi: 10.1016/S1098-612X(99)90065-7.
2
A minimal regulatory region maintains constitutive expression of the max gene.一个最小调控区域维持max基因的组成型表达。
Mol Cell Biol. 1997 Mar;17(3):1037-48. doi: 10.1128/MCB.17.3.1037.