Bell S D, Lau K Y, Sniderman K W
Department of Radiology, Toronto Hospital, Ontario, Canada.
J Vasc Interv Radiol. 1995 Jul-Aug;6(4):531-6. doi: 10.1016/s1051-0443(95)71129-0.
To assess the efficacy and safety of synchronous embolization of the gastroduodenal artery (GDA) and inferior pancreaticoduodenal artery (IPDA) in patients with massive duodenal hemorrhage.
All cases of synchronous embolization of the GDA and IPDA at the authors' hospital between 1980 and 1989 were retrospectively reviewed.
Bleeding was successfully controlled acutely in all six patients who underwent synchronous embolization. Clinical evidence of recurrent hemorrhage was found in two patients, but repeat angiography showed no extravasation of contrast material. Three patients died within 30 days of embolotherapy. In one patient who also received an infusion of vasopressin, postmortem evidence of pancreatic necrosis was found.
Synchronous embolization of the GDA and IPDA can be an effective treatment for continuing duodenal hemorrhage after failed endoscopic therapy in patients considered a poor surgical risk. The procedure should be undertaken only as a lifesaving measure due to the risk of pancreatic and duodenal necrosis.
评估胃十二指肠动脉(GDA)和胰十二指肠下动脉(IPDA)同步栓塞术治疗十二指肠大出血患者的疗效和安全性。
回顾性分析1980年至1989年间在作者所在医院接受GDA和IPDA同步栓塞术的所有病例。
接受同步栓塞术的6例患者出血均得到急性成功控制。2例患者出现复发出血的临床证据,但再次血管造影未显示造影剂外渗。3例患者在栓塞治疗后30天内死亡。在1例同时接受血管加压素输注的患者中,尸检发现胰腺坏死证据。
对于手术风险高且内镜治疗失败的十二指肠持续出血患者,GDA和IPDA同步栓塞术可能是一种有效的治疗方法。由于存在胰腺和十二指肠坏死的风险,该手术仅应作为挽救生命的措施进行。