酶：化学与生物化学
Enzymes: chemistry and biochemistry.
作者信息
Jeffery J
机构信息
Department of Molecular and Cell Biology, University of Aberdeen, Marischal College, Scotland, UK.
出版信息
EXS. 1995;73:79-104. doi: 10.1007/978-3-0348-9061-8_5.
PMID:7579980
Abstract
Basic principles underlying enzyme action are considered. Catalytic antibodies (abzymes), catalytic RNA (ribozymes), and non-biological counterparts of enzyme-catalyzed reactions are mentioned. Enzyme evolution is considered in terms of divergence, convergence, and lateral gene transfer.
摘要
本文探讨了酶作用的基本原理。文中提及了催化抗体（酶抗体）、催化RNA（核酶）以及酶催化反应的非生物对应物。从趋异、趋同和横向基因转移的角度对酶的进化进行了探讨。
相似文献
1
Enzymes: chemistry and biochemistry.酶：化学与生物化学
EXS. 1995;73:79-104. doi: 10.1007/978-3-0348-9061-8_5.
2
Catalysing new reactions during evolution: economy of residues and mechanism.在进化过程中催化新反应：残基经济性与机制
J Mol Biol. 2003 Aug 22;331(4):829-60. doi: 10.1016/s0022-2836(03)00734-4.
3
Understanding nature's catalytic toolkit.了解大自然的催化工具包。
Trends Biochem Sci. 2005 Nov;30(11):622-9. doi: 10.1016/j.tibs.2005.09.006. Epub 2005 Oct 7.
4
Coenzymes as coribozymes.作为辅酶的核酶。
Biochimie. 2002 Sep;84(9):877-88. doi: 10.1016/s0300-9084(02)01404-9.
5
Analysis of catalytic residues in enzyme active sites.酶活性位点中催化残基的分析。
J Mol Biol. 2002 Nov 15;324(1):105-21. doi: 10.1016/s0022-2836(02)01036-7.
6
Generation of new enzymes via covalent modification of existing proteins.通过对现有蛋白质进行共价修饰来生成新酶。
Chem Rev. 2001 Oct;101(10):3081-111. doi: 10.1021/cr000059o.
7
Structural convergence in the active sites of a family of catalytic antibodies.一类催化抗体活性位点的结构趋同
Science. 1997 Feb 21;275(5303):1140-2. doi: 10.1126/science.275.5303.1140.
8
Catalytic cleavage of cis- and trans-acting antigenomic delta ribozymes in the presence of various divalent metal ions.在各种二价金属离子存在的情况下，顺式和反式作用的反基因组δ核酶的催化切割。
Nucleic Acids Res. 2001 Nov 1;29(21):4482-92. doi: 10.1093/nar/29.21.4482.
9
Enzyme models: design and selection.酶模型：设计与选择
Curr Opin Chem Biol. 1997 Dec;1(4):483-90. doi: 10.1016/s1367-5931(97)80042-7.
10
Immunological origins of binding and catalysis in a Diels-Alderase antibody.狄尔斯-阿尔德酶抗体中结合与催化的免疫学起源
Science. 1998 Mar 20;279(5358):1929-33. doi: 10.1126/science.279.5358.1929.
引用本文的文献
1
On the failure of de novo-designed peptides as biocatalysts.关于从头设计的肽作为生物催化剂的失败情况。
Proc Natl Acad Sci U S A. 1996 Oct 15;93(21):11428-34. doi: 10.1073/pnas.93.21.11428.
Zotero 插件