Observations on the physostigmine syndrome in patients with Alzheimer's disease.
作者信息
Wirkowski E, Prohovnik I, Young W L
机构信息
Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
出版信息
J Neuropsychiatry Clin Neurosci. 1991 Winter;3(1):73-5. doi: 10.1176/jnp.3.1.73.
PMID:7580177
Abstract
The authors present two patients with Alzheimer's disease who each received a single intravenous dose of physostigmine. Subjective complaints and mood changes were disproportional with objectively verified physiological side effects. Such observations may contribute to an understanding of affective disorders and should receive more attention in future studies of cholinesterase inhibitors.
摘要
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