Pomerleau O F, Pomerleau C S
Department of Psychiatry, University of Michigan, Ann Arbor 48105, USA.
J Subst Abuse. 1989;1(3):253-7.
There has been a notable lack of dialogue between neuroscientists, who use nicotine in their work as they would any other pharmacological tool, and public policy and health researchers, who view nicotine dependence with increasing dismay and see the continued use of tobacco products as a modern day scourge. This special journal issue attempts to foster communication among nicotine researchers working along the continuum from basic to applied science. An additional objective is to convey a sense for the special problems and opportunities in the study of nicotine and tobacco use that may be of general interest to those concerned with substance abuse. The articles that follow explore two themes, (1) nicotine as a tool to probe neural activity, and (2) tobacco use as a health hazard and societal problem, by examining nicotine from pharmacochemical, biobehavioral, and econo-social perspectives. The rationale for the integration is that there may be benefits from viewing nicotine in a context broader than those dictated by custom and technological specialization.
神经科学家在工作中像使用其他药理学工具一样使用尼古丁，而公共政策和健康研究人员则越来越惊恐地看待尼古丁成瘾，并将烟草制品的持续使用视为现代社会的一大祸害。在这两者之间，明显缺乏对话。本期特刊试图促进从基础科学到应用科学的尼古丁研究人员之间的交流。另一个目标是传达尼古丁和烟草使用研究中一些特殊的问题和机遇，这些可能会引起那些关注药物滥用问题的人的普遍兴趣。接下来的文章探讨了两个主题：（1）尼古丁作为探测神经活动的工具；（2）烟草使用作为一种健康危害和社会问题。文章从药物化学、生物行为学和经济社会学的角度审视尼古丁，整合这些视角的基本原理是，从比习惯和技术专业化所限定的更广泛的背景中看待尼古丁可能会有好处。
