Petros P E, Ulmsten U
Department of Gynaecology, Royal Perth Hospital, Western Australia.
Neurourol Urodyn. 1995;14(4):337-46; discussion 346-50. doi: 10.1002/nau.1930140406.
The aim of the study was to determine the contribution of intra-abdominal pressure transmission to urinary continence in the female. Five patients with genuine stress incontinence (GSI) were studied. Pressure transmission was measured in equivalent positions inside and outside the urethra and bladder during the Intravaginal Slingplasty procedure, a surgical operation used for treatment of urinary incontinence, and performed under local anaesthesia. A 6 mm diameter channel was created alongside the urethra. Two separate microtransducer catheters appropriately marked for length were inserted, one inside the urethra, and the other inside the described channel. With the vaginal hammock intact, an average of 10 simultaneous pressure measurements were made intraoperatively in response to coughing and straining in equivalent positions inside the urethra, and directly outside. Significantly higher pressure readings were found inside the urethra (P = 0.0025), indicating that an active component within the urethra may have created this pressure rise. After opening out two suburethral vaginal flaps, large quantities of urine were lost on coughing in all patients. Continence was achieved on tightening the suburethral vagina, indicating that an adequately tight vaginal hammock is a critical element in the continence process. The findings of this study question intraabdominal pressure as a mechanism contributing to continence, but support an alternative mechanism, musculovaginal closure of the urethra.
该研究的目的是确定腹内压传递对女性尿失禁的影响。研究了5例真性压力性尿失禁(GSI)患者。在阴道吊带成形术(一种用于治疗尿失禁的外科手术,在局部麻醉下进行)过程中,测量了尿道和膀胱内外等效位置的压力传递。在尿道旁创建了一个直径6毫米的通道。插入两根分别标有长度的微型换能器导管,一根插入尿道内,另一根插入上述通道内。在阴道吊带完整的情况下,术中平均在尿道内和直接在尿道外的等效位置进行了10次同时的压力测量,以应对咳嗽和用力。在尿道内发现压力读数明显更高(P = 0.0025),表明尿道内的一个活性成分可能导致了这种压力升高。打开两个尿道下阴道瓣后,所有患者在咳嗽时都大量漏尿。收紧尿道下阴道后实现了控尿,表明足够紧的阴道吊带是控尿过程中的一个关键因素。这项研究的结果对腹内压作为一种导致控尿的机制提出了质疑,但支持了另一种机制,即尿道的肌肉-阴道闭合。