[2,4-二硝基苯酚对实验性甲状腺功能亢进时肌肉收缩温度效应的影响]
[The influence of 2,4-dinitrophenol on the temperature effect of muscle contraction in experimental hyperthyroidism].
作者信息
Sobolev V I, Makhsudov M S, Merkhelevich L G, Chali G, Rabo G, Dakoshta M
出版信息
Fiziol Zh Im I M Sechenova. 1995 Mar;81(3):80-4.
PMID:7581564
Abstract
Experimental hyperthyroidism reduced the force of muscle contraction leaving unaltered the temperature of the contracting skeletal muscles in rats. The thermal effect therefore was increased as per the unit of developing force. Administration of 2,4-dinitrophenol increased the temperature effect in intact rats and exerted no influence in the hyperthyroid animals.
摘要
实验性甲状腺功能亢进降低了肌肉收缩力，而大鼠收缩的骨骼肌温度未发生改变。因此，按单位发育力计算，热效应增加。给予2,4-二硝基苯酚可增加正常大鼠的温度效应，而对甲状腺功能亢进动物无影响。
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