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用肺动脉自体移植修复复杂的左心室流出道梗阻

Repair of complex left ventricular outflow tract obstruction with a pulmonary autograft.

作者信息

Daenen W J

机构信息

Department of Cardiac Surgery Gasthuisberg University Hospital, Leuven, Belgium.

出版信息

J Heart Valve Dis. 1995 Jul;4(4):364-7.

PMID:7582142
Abstract

The surgical relief of complex multilevel left ventricular outflow tract (LVOT) obstruction remains a challenging surgical problem. We present a new operation which combines the concepts of aortoventriculoplasty, extended aortic root replacement and the use of a pulmonary autograft. Sixteen patients underwent this operation: 11 patients after previous attempts to relieve diffuse subvalvular stenosis and five patients who presented excessive gradients over an outgrown aortic valve prosthesis. All patients, except one survived the operation. One patient developed massive right ventricular infarction and was transplanted after five days. Another patient developed complete heart block and transient tricuspid regurgitation after a septal infarction. One patient remained in congestive heart failure and died suddenly after 17 months. All other patients are in NYHA class I after a mean follow up of 21 +/- 12 months. One patient developed progressive dilatation of the neo-aortic root and was reoperated four years after initial surgery. All other patients showed laminar flow in the LVOT and excellent function of the autograft and homograft valve at follow up. This operation might present a durable or even a definitive solution in the management of these complex left ventricular outflow tract obstructions.

摘要

复杂多节段左心室流出道(LVOT)梗阻的外科缓解仍然是一个具有挑战性的外科问题。我们提出了一种新的手术方法,该方法结合了主动脉心室成形术、扩大主动脉根部置换术的概念以及自体肺动脉移植的应用。16例患者接受了该手术:11例患者此前曾尝试缓解弥漫性瓣下狭窄,5例患者在主动脉瓣假体生长过度后出现过高压力阶差。除1例患者外,所有患者均手术存活。1例患者发生大面积右心室梗死,5天后接受移植。另1例患者在间隔梗死后发生完全性心脏传导阻滞和短暂性三尖瓣反流。1例患者仍处于充血性心力衰竭状态,17个月后突然死亡。所有其他患者在平均随访21±12个月后均处于纽约心脏协会(NYHA)I级。1例患者出现新主动脉根部进行性扩张,在初次手术后4年再次手术。所有其他患者在随访时左心室流出道均显示层流,自体移植瓣膜和同种异体瓣膜功能良好。该手术可能为这些复杂的左心室流出道梗阻的治疗提供一种持久甚至决定性的解决方案。

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