Marais R, Marshall C
CRC Centre for Cell and Molecular Biology, Institute of Cancer Research, London, UK.
Structure. 1995 Aug 15;3(8):751-3. doi: 10.1016/s0969-2126(01)00209-x.
The crystal structures of 14-3-3 proteins reveal that they form dimers with a deep groove running along the length of the dimer. The location of conserved residues in this groove suggests that it plays an essential role in the adaptor functions of these proteins.
14-3-3蛋白的晶体结构显示,它们形成二聚体,二聚体的长度方向有一条深沟。该沟中保守残基的位置表明,它在这些蛋白质的衔接子功能中起重要作用。