Raiser F, Hinder R A, McBride P J, Katada N, Filipi C J
Department of Surgery, Creighton University School of Medicine, Omaha, Nebraska, USA.
Chest Surg Clin N Am. 1995 Aug;5(3):437-48.
Patients with severe GERD resistant to medical therapy are benefited greatly by laparoscopic fundoplication provided that there is careful preoperative patient selection and evaluation. Preoperative evaluation should include contrast esophagography, EGD with biopsies, stationary manometry, and 24-hour pH analysis. Significant esophageal shortening or severe dysplasia are contraindications to laparoscopic fundoplication. A short, loose Nissen fundoplication should be performed in patients with adequate esophageal body function, whereas patients with esophageal dysmotility should be offered a partial fundoplication such as the Toupet procedure. If these guidelines are followed, long-term good results can be expected, with minimal complications, and all of the advantages of the minimally invasive approach.
对于药物治疗无效的重度胃食管反流病(GERD)患者,只要术前对患者进行仔细筛选和评估,腹腔镜胃底折叠术会使其受益匪浅。术前评估应包括食管造影、内镜下活检、静态测压以及24小时pH值分析。明显的食管缩短或严重发育异常是腹腔镜胃底折叠术的禁忌证。对于食管体部功能正常的患者,应施行短而宽松的nissen胃底折叠术,而对于食管动力障碍患者,则应采用诸如Toupet手术等部分胃底折叠术。如果遵循这些指导原则,有望获得长期良好效果,并发症极少,且具备微创方法的所有优点。