Suter M, Bettschart V
Service de chirurgie, Centre hospitalier universitaire vaudois, Lausanne.
Schweiz Med Wochenschr. 1998 Nov 14;128(46):1813-21.
Indications for surgery in gastrooesophageal reflux disease (GERD) have decreased significantly since the introduction of proton pump inhibitors. At the same time there has been renewed surgical interest in this disease triggered by the development of laparoscopy. We present our results with laparoscopic treatment of GERD and the change in our surgical approach to the condition during the past few years.
All patients admitted to the surgical department underwent prior evaluation by a gastroenterologist. Indications for surgery were resistance to medical therapy in 30 cases, recurrence of GERD after cessation of treatment in 25 cases and personal preference of the patient when maintenance therapy was necessary in 6 cases. The data were reviewed and the patients contacted during the first trimester of 1998 to evaluate long-term results.
63 patients were operated on between 1991 and July 1997. Rossetti-Nissen fundoplication was performed routinely until March 1995. Thereafter, the type of antireflux surgery has been chosen according to the preoperative evaluation of the patients, including endoscopy, oesophageal manometry and gastric emptying studies. There was no mortality and, except for one case, only minor morbidity. Four patients required reoperation, two for severe gas bloat syndrome and two for recurrence of GERD. Overall, the long-term follow-up shows that 93 patients are satisfied or very satisfied with their outcome (Visick 1 or 2). 5% of the patients need daily medication for heartburn, 5% complain of occasionally disturbing dysphagia, and 12% of sometimes distressing gas bloat. More patients have gas bloat after the Rossetti-Nissen procedure than after the Nissen or Toupet fundoplications.
The enthusiasm of surgeons for the laparoscopic approach to GERD has prompted renewed interest in the pathophysiology of the disease. Consequently, indications for surgery are better defined, surgical technique is chosen according to the individual patient based on objective preoperative studies and follow-up has improved. In this setting, laparoscopic fundoplication represents an effective treatment for GERD. It is associated with lower postoperative morbidity than open surgery and represents the first choice when surgery is indicated.
自从质子泵抑制剂问世以来,胃食管反流病(GERD)的手术指征已显著减少。与此同时,腹腔镜技术的发展引发了对该疾病新的手术治疗兴趣。我们展示了过去几年中GERD腹腔镜治疗的结果以及我们对该病手术方法的改变。
所有入住外科的患者均事先由胃肠病学家进行评估。手术指征包括30例药物治疗无效、25例治疗停止后GERD复发以及6例在需要维持治疗时患者的个人偏好。回顾了这些数据,并在1998年第一季度与患者取得联系以评估长期结果。
1991年至1997年7月间对63例患者进行了手术。1995年3月之前常规进行Rossetti-Nissen胃底折叠术。此后,根据患者的术前评估(包括内镜检查、食管测压和胃排空研究)选择抗反流手术类型。无死亡病例,除1例之外,仅出现轻微并发症。4例患者需要再次手术,2例因严重的气胀综合征,2例因GERD复发。总体而言,长期随访显示93例患者对其结果满意或非常满意(Visick 1级或2级)。5%的患者需要每日服用治疗烧心的药物,5%的患者抱怨偶尔出现困扰的吞咽困难,12%的患者有时会出现令人苦恼的气胀。与Nissen或Toupet胃底折叠术相比,Rossetti-Nissen手术术后出现气胀的患者更多。
外科医生对GERD腹腔镜手术方法的热情促使人们对该疾病的病理生理学重新产生兴趣。因此,手术指征得到了更好的界定,根据术前客观研究为个体患者选择手术技术,并且随访情况有所改善。在这种情况下,腹腔镜胃底折叠术是GERD的一种有效治疗方法。与开放手术相比,它术后并发症发生率更低,是有手术指征时的首选方法。