Wolffe A P
Laboratory of Molecular Embryology, National Institute of Child Health and Human Development, NIH, Bethesda, Maryland 20892-2710, USA.
Curr Biol. 1995 May 1;5(5):452-4. doi: 10.1016/s0960-9822(95)00088-1.
Highly variant histones are targeted to specialized chromatin domains, such as the centromere where they have an essential role in the segregation of sister chromatids at mitosis.
高度可变的组蛋白靶向于特殊的染色质结构域,例如着丝粒,在有丝分裂过程中,它们在姐妹染色单体的分离中发挥着重要作用。