Karpeh M S, Brennan M F
Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
Curr Opin Gen Surg. 1994:125-30.
Over the past 30 years, numerous major centers have published analyses of potential factors influencing survival following resection of gastric cancer. The independent significance of depth of tumor penetration and lymph node status has been consistently documented. With proper staging, we know which patients are most likely to die of their disease. Unfortunately, adjuvant treatment in surgical resection has not altered patient outcome. Emphasis should now be on selecting the patients who should receive radical surgery for cure, adjuvant therapy with a hope for cure, or palliation. This brief review concentrates on recent developments in our ability to stage patients preoperatively, developments that may change the way we approach the patient with stomach cancer in the future.
在过去30年里，众多主要中心都发表了关于影响胃癌切除术后生存的潜在因素的分析。肿瘤浸润深度和淋巴结状态的独立重要性已得到一致证实。通过适当的分期，我们知道哪些患者最有可能死于其疾病。不幸的是，手术切除中的辅助治疗并未改变患者的预后。现在应重点关注选择那些应接受根治性手术以治愈、有望通过辅助治疗治愈或姑息治疗的患者。这篇简短的综述集中于我们术前对患者进行分期能力的最新进展，这些进展可能会改变我们未来处理胃癌患者的方式。
