Matory Y L
Brigham and Women's Hospital, Surgical Oncology Division, Boston, MA 02115, USA.
Curr Opin Gen Surg. 1994:217-23.
There have been several new developments in breast cancer research. Investigators are closer to identifying the breast cancer gene, which may aid in the diagnosis and treatment of the disease. The more established routine of screening mammography has been questioned by the results of the Canadian National Breast Screening Study. Many authors challenge this study's validity. Largely because of screening mammography, noninvasive breast cancer is one of the most frequently diagnosed types of breast cancer. The treatment options for noninvasive breast cancers are discussed along with recent publications. The option of breast-conserving therapy for early stage cancers is also reviewed. Recent investigators have sought to identify the most appropriate patients for breast conservation. This overview also discusses treatment options for advanced cancers and the use of hormonal therapy for all patients with breast cancer.
乳腺癌研究有了几项新进展。研究人员更接近识别出乳腺癌基因，这可能有助于该疾病的诊断和治疗。加拿大全国乳腺癌筛查研究的结果对更为成熟的乳腺钼靶筛查常规做法提出了质疑。许多作者对这项研究的有效性提出质疑。很大程度上由于乳腺钼靶筛查，非侵袭性乳腺癌是最常被诊断出的乳腺癌类型之一。文中讨论了非侵袭性乳腺癌的治疗选择以及近期的出版物。还回顾了早期癌症保乳治疗的选择。近期的研究人员试图确定最适合保乳治疗的患者。本综述还讨论了晚期癌症的治疗选择以及所有乳腺癌患者的激素治疗应用。
