Roslyn J J
Medical College of Pennsylvania, Philadelphia, USA.
Curr Opin Gen Surg. 1993:265-70.
The scope and importance of biliary infections from both a clinical and scientific perspective is rapidly changing. During this past year, considerable attention in the literature has focused on infections that are increasing in frequency in the United States and throughout the world, as a result of evolving demographics and continued spread of the acquired immunodeficiency syndrome epidemic. Pyogenic cholangitis remains a challenge for us to treat and significant controversy remains regarding optimal management. The myriad hepatobiliary manifestations of human immunodeficiency virus infection have led to a resurgence in the interest in parasitic and viral infections. Our understanding of infections and their pathogenesis and sequelae has progressed, although there are still many important questions that remain unanswered.
从临床和科学角度来看，胆道感染的范围和重要性正在迅速变化。在过去一年中，由于人口结构的演变以及获得性免疫缺陷综合征疫情的持续蔓延，美国乃至全球范围内发病率不断上升的感染在文献中受到了相当大的关注。化脓性胆管炎对我们来说仍是一个治疗难题，关于最佳治疗方案也仍存在重大争议。人类免疫缺陷病毒感染的众多肝胆表现引发了对寄生虫和病毒感染兴趣的再度兴起。尽管仍有许多重要问题尚未得到解答，但我们对感染及其发病机制和后遗症的理解已经取得了进展。
