Deitch E A
Louisiana State University Medical Center, Shreveport, USA.
Curr Opin Gen Surg. 1993:85-91.
That the gastrointestinal tract performs important immunologic, metabolic, and barrier functions, in addition to nutrient digestion and absorption, has recently become clear, as have the potential deleterious consequences of loss of mucosal barrier function. Because of the potentially important relationship between nutrition and gut barrier function, this area has received increasing clinical and experimental attention over the past several years. Consequently, this review focuses on how nutrition can modulate the integrity of the gut mucosal barrier. Special attention will be given to the biology of normal intestinal barrier function, as well as to studies investigating the role of nutritionally related variables on the gut mucosal barrier.
胃肠道除了具有营养物质消化和吸收功能外，还发挥着重要的免疫、代谢和屏障功能，这一点最近已变得清晰明了，黏膜屏障功能丧失的潜在有害后果亦是如此。由于营养与肠道屏障功能之间可能存在重要关系，在过去几年中，该领域受到了越来越多的临床和实验关注。因此，本综述重点关注营养如何调节肠道黏膜屏障的完整性。将特别关注正常肠道屏障功能的生物学特性，以及研究营养相关变量对肠道黏膜屏障作用的相关研究。
