人类21号染色体的60个新序列标签位点（STSs）。
Sixty new STSs (sequence-tagged sites) of human chromosome 21.
作者信息
Tanahashi H, Ito T, Hattori M, Ohira M, Ohki M, Tashiro K, Sakaki Y
机构信息
Human Genome Center, University of Tokyo, Japan.
出版信息
DNA Res. 1994;1(2):85-9. doi: 10.1093/dnares/1.2.85.
PMID:7584032
Abstract
From human chromosome 21-specific libraries, 22 SfiI linking clones and 38 P1 clones were isolated and regionally mapped on the chromosome. The terminal sequences of these clones were determined and pairs of PCR primers were generated which could specifically amplify the sequenced regions. These sequence-tagged sites (STSs) should be useful for constructing a high resolution map of human chromosome 21.
摘要
从人类21号染色体特异性文库中，分离出22个SfiI连接克隆和38个P1克隆，并将它们定位到该染色体的相应区域。测定了这些克隆的末端序列，并设计了成对的PCR引物，这些引物能够特异性扩增已测序区域。这些序列标签位点（STS）对于构建人类21号染色体的高分辨率图谱应该是有用的。
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