采用高压液相色谱法对药物剂型中的氯噻酮进行定量测定。
Quantitative determination of chlorthalidone in pharmaceutical dosage forms by high-pressure liquid chromatography.
作者信息
O'Hare M J, Tan E, Moody J E
出版信息
J Pharm Sci. 1979 Jan;68(1):106-8. doi: 10.1002/jps.2600680136.
PMID:758442
Abstract
A reliable and selective high-pressure liquid chromatographic procedure for the quantitative determination of chlorthalidone in pharmaceutical dosage forms is described. A comparison of this stability-indicating procedure with the USP spectrophotometric assay is presented for chlorthalidone tablets and chlorhalidone tablets containing reserpine.
摘要
本文描述了一种可靠且具选择性的高效液相色谱法，用于定量测定药物剂型中的氯噻酮。文中还给出了该稳定性指示方法与美国药典分光光度法测定含利血平的氯噻酮片和氯噻酮片的比较结果。
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