蛋白质结构、序列同源性与氨基酸组成之间的关系。
Relation between protein structure, sequence homology and composition of amino acids.
作者信息
Mayoraz E, Dubchak I, Muchnik I
机构信息
RUTCOR-Rutgers University's Center for Operations Research, New Brunswick, NJ 08903-5062, USA.
出版信息
Proc Int Conf Intell Syst Mol Biol. 1995;3:240-8.
PMID:7584443
Abstract
A method of quantitative comparison of two classifications rules applied to protein folding problem is presented. Classification of proteins based on sequence homology and based on amino acid composition were compared and analyzed according to this approach. The coefficient of correlation between these classification methods and the procedure of estimation of robustness of the coefficient are discussed.
摘要
提出了一种对应用于蛋白质折叠问题的两种分类规则进行定量比较的方法。根据这种方法，对基于序列同源性和基于氨基酸组成的蛋白质分类进行了比较和分析。讨论了这些分类方法之间的相关系数以及该系数稳健性的估计过程。
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