del Olmo J A, Añón C, Llovet F, Serra M A, Wassel A, Rodrigo J M
Unidad de Hepathología, Hospital Clinico Universitario, Equipo de Salud del Centro Penitenciario de Preventivos, Picassent, Valencia.
Gastroenterol Hepatol. 1995 Oct;18(8):405-9.
The prisoner population of the penitentiaries presents an elevated prevalence of hepatitis B virus (HBV) and human immunodeficiency type 1 (HIV-1) infection markers. In the last few years different measures have been developed to prevent infection. This study evaluates whether there have been changes in the prevalence of infection by these virus over the last few years within a penitentiary. A group of prisoners (n = 163) studied in 1985 were therefore compared with another group (n = 750) studied in 1992. Demographic, social, risk and penitentiary factors were included. In each of the subjects studied alanine aminotransferase (ALT), hepatitis B virus (HBsAG, antiHBs and antiHBc) and anti-HIV-1 markers were determined. It was globally observed that following the 7 years between the two studies there was a decrease in the prevalence of HBV (X = 14.63, p = 0.0001, OR = 2; CI 95%: 1.38-2.9), which was mainly observed in the group of prisoners with no drug addiction habits. No differences were observed with regard to the prevalence of anti-HIV-1 which remained similar among the IV drug consumers and not consumers (64% and 66.6% in 1985 and 1992, respectively). In conclusion, from 1985 to 1992 a decrease has been observed in the prevalence of hepatitis B virus infection in the penitentiary population while the prevalence of anti-HIV-1 has remained unchanged.
监狱中的囚犯群体呈现出较高的乙肝病毒(HBV)和1型人类免疫缺陷病毒(HIV-1)感染标志物患病率。在过去几年中,已制定了不同的预防感染措施。本研究评估了过去几年内一所监狱中这些病毒的感染患病率是否发生了变化。因此,将1985年研究的一组囚犯(n = 163)与1992年研究的另一组囚犯(n = 750)进行了比较。纳入了人口统计学、社会、风险和监狱因素。对每个研究对象测定了丙氨酸转氨酶(ALT)、乙肝病毒(HBsAG、抗HBs和抗HBc)以及抗HIV-1标志物。总体观察发现,在两项研究间隔的7年中,HBV患病率有所下降(X = 14.63,p = 0.0001,OR = 2;95%置信区间:1.38 - 2.9),这主要在没有吸毒习惯的囚犯群体中观察到。在抗HIV-1患病率方面未观察到差异,在静脉吸毒者和非吸毒者中该患病率保持相似(1985年和1992年分别为64%和66.6%)。总之,从1985年到1992年,监狱人群中乙肝病毒感染患病率有所下降,而抗HIV-1患病率保持不变。