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[同一家族中两名患者的青少年息肉病]

[Juvenile polyposis in 2 patients of the same family].

作者信息

Alcaín G, Guillén P, Soria M J, Rendón P, Alonso E, Garcia C

机构信息

Servicio de Aparato Digestivo, Hospital Universitario Puerta del Mar, Cádiz.

出版信息

Gastroenterol Hepatol. 1995 Oct;18(8):417-9.

PMID:7584781
Abstract

Two cases of juvenile familiar polyposis (one 40-year-old male and his 14-year-old daughter) are presented. The girl presented intermittent rectal bleeding since the age of 10 with growth retardation and chronic anemia. The child was treated by colectomy with more than 100 juvenile polyps without adenomatous alterations being observed in the surgical specimen. Juvenile gastric polyps were also endoscopically observed. The father underwent sigmoidectomy for a adenomatous polyp of this localization. Later review of the surgical specimen demonstrated a juvenile polyp with zones of adenomatous alterations. The diagnostic difficulties of this rare entity and the therapeutic options available are discussed.

摘要

本文报告两例青少年家族性息肉病(一例40岁男性及其14岁女儿)。该女孩自10岁起出现间歇性直肠出血,伴有生长发育迟缓及慢性贫血。患儿接受了结肠切除术,手术标本中有100多个青少年息肉,未观察到腺瘤样改变。内镜检查还发现了青少年胃息肉。父亲因该部位的腺瘤性息肉接受了乙状结肠切除术。后来对手术标本的复查显示有一个带有腺瘤样改变区域的青少年息肉。讨论了这种罕见疾病的诊断难点及可用的治疗方案。

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